Inflammation's Dark Side: How Chronic Inflammation Drives Aging
The quiet inflammatory fire that burns throughout aging—and how to dampen it
Proteostasis: Why Protein Quality Control Matters for Longevity
Your cells run a constant protein quality control operation—and its decline may be central to why we age.
Stem Cell Exhaustion: Why Tissue Repair Slows With Age
Your body's repair crews are aging—but research suggests they might be revived
Sleep Architecture and Longevity: Why Deep Sleep Declines With Age
Deep sleep declines decades before disease appears—and the repair processes it enables don't have a backup system.
Epigenetic Clocks: Measuring Your True Biological Age
DNA methylation patterns reveal your biological age—and suggest it might be changeable
Glycation and AGEs: The Sugar-Damage Connection to Aging
How sugar molecules permanently modify your proteins, driving aging from skin to arteries
The Gut-Aging Axis: How Your Microbiome Influences Longevity
Your gut bacteria may hold surprising keys to how quickly you age—and unlike genetics, they respond to what you do today.
Zombie Cells: How Senescent Cells Accelerate Aging
Discover how damaged cells that refuse to die poison surrounding tissue and drive aging—and what emerging science may do about them.
Caloric Restriction Without Starvation: What Actually Works
Decades of research reveal how strategic eating patterns activate cellular repair—and where restriction crosses from beneficial to dangerous.
Mitochondrial Dysfunction: When Your Cellular Power Plants Fail
Your cells contain thousands of power plants that determine how you age—and their maintenance is more within your control than you might expect.
Autophagy: How Cellular Self-Eating Promotes Longevity
Your cells have a built-in cleanup crew that slows with age—here's what science says about keeping it active.
The Sirtuins: Master Regulators of Cellular Longevity
These seven proteins sense cellular energy status and trigger survival programs that may determine how well your cells age.
Why Your Cells Stop Dividing: The Hayflick Limit Explained
Your cells count every division through shrinking telomeres—understanding this biological countdown reveals both why we age and how longevity research navigates the cancer tradeoff.
NAD+ Decline: The Energy Currency Crisis of Aging
Why your cells lose their essential energy coenzyme with age—and what current science reveals about restoring it