Neurogenesis in Adults: Facts and Controversies
The contested search for new neurons in the adult human brain, and why methodology is the real battleground
Mirror Neurons: What Survived the Hype
After decades of inflated claims, motor resonance finds its real place in social cognition
Cognitive Reserve: Why Some Brains Age Better
How neural efficiency, synaptic redundancy, and flexible compensation buffer the brain against aging pathology
Metacognition: The Art of Knowing What You Know
The anterior prefrontal cortex computes confidence separately from cognition—understanding this architecture reveals why psychiatric conditions systematically distort self-knowledge.
Anxiety Sensitivity: The Fear of Fear Itself
Why some people fear not just danger, but the sensation of being afraid—and how this specific vulnerability shapes panic pathology.
Dissociation: From Defense Mechanism to Neural Mechanism
How neuroscience is mapping the neural architecture of fragmented consciousness and revealing dissociation's developmental origins.
Learned Helplessness: How Uncontrollability Reshapes the Brain
When the prefrontal cortex fails to detect control, the brain defaults to passivity—rewriting our understanding of depression's origins.
Why Antidepressants Take Weeks to Work: The Neuroplasticity Explanation
The weeks of waiting for antidepressant response reflect brain-level renovation, not pharmacological inadequacy—understanding the neuroplasticity cascade explains why recovery cannot be rushed.
Attention Networks: Why Focus Is Not One Thing
Dissecting alerting, orienting, and executive control—three distinct neural systems that explain ADHD heterogeneity and brain training's broken promises
Interoception: The Hidden Sense Underlying Emotion Regulation
How the brain's predictions about your body construct your emotional reality
The Neuroscience of Self-Criticism: Internal Threat Processing
Research reveals that attacking yourself mentally triggers the same brain systems as facing an actual predator
The Prefrontal Paradox: Why Overthinking Undermines Performance
Your brain's executive center can sabotage the very skills it oversees—understanding why offers a path out.
Sleep Architecture and Memory: What Each Stage Contributes
Each sleep stage runs distinct memory programs—understanding their coordination reveals why architecture matters as much as duration
The Gut-Brain Axis in Mental Health: Separating Hype from Evidence
What the microbiome-mental health connection actually shows versus what headlines claim—a rigorous assessment for evidence-based practitioners
The Science of Placebo: More Than Just Expectation
Neuroimaging reveals placebo as genuine pharmacology—endogenous neurochemistry, conditioned responses, and contextual factors that can be ethically harnessed in clinical practice.
The Neuroscience of Rumination: Breaking the Loop
Understanding the neural circuits that trap minds in recursive negativity reveals why some interventions fail and how to match treatments to mechanisms
Memory Reconsolidation: The Science of Updating Trauma
How reactivated trauma memories become temporarily modifiable—and what therapeutic protocols successfully exploit this window to achieve lasting change.
Why Your Brain Resists Change Even When You Want It
Neuroscience reveals why willpower fails against habit circuitry and what actually works for lasting behavioral change
Why Exposure Therapy Fails and How to Fix It
Understanding why fear memories persist reveals precise procedural modifications that transform exposure therapy from temporary relief into lasting freedom.
Neuroplasticity After 40: What Research Actually Shows
A critical analysis of what adult brain plasticity research actually demonstrates—beyond both pessimistic aging myths and oversimplified rewiring promises.
The Inflammatory Theory of Depression: Evidence and Limitations
Examining whether immune dysregulation causes depression in specific patient subgroups—and why anti-inflammatory treatments show promise only with proper biomarker stratification.